Case Presentation: A 26-year-old otherwise healthy female was prescribed trimethoprim-sulfamethoxazole (TMP-SMX) for a recurring, spontaneously draining vaginal mass below her urethra with inguinal adenopathy. 5 days after starting TMP-SMX, she developed a full-body rash, fever, myalgia, nausea, and a depressed WBC of 2.4 K/mcL. Possible drug fever was suspected and TMP-SMX was discontinued and covered [...]

Case Presentation: A 31-year-old male with no significant past medical history presented with fever, chills, night sweats, and rash. One week prior, he underwent incision and drainage of a perirectal abscess and was started on a 7-day course of trimethoprim/sulfamethoxazole (TMP-SMX). On the second day following the procedure, he developed fevers, chills, night sweats, and [...]