Case Presentation: A previously-healthy 72-year-old woman presented with two weeks of progressive fatigue. Laboratory testing revealed a white blood cell (WBC) count of 140×109/L, hemoglobin 8g/dL, platelets 30×109/L. Peripheral blood smear showed greater than 90% blasts and promyelocytes. Chest radiograph and transthoracic echocardiogram (TTE) were unremarkable. She was started on all-trans retinoic acid (ATRA), idarubicin (IDA), [...]

Case Presentation: A 37-year-old woman with history of ulcerative colitis and focal nodular hyperplasia (FNH) of the liver presented with right upper quadrant (RUQ) abdominal pain. An extensive workup including endoscopic retrograde cholangiopancreatography (ERCP) eventually diagnosed primary sclerosing cholangitis (PSC).  However, review of systems was also significant for epistaxis.  Family history was significant for father [...]

Case Presentation: A 54 year old female with history of SLE, ESRD on hemodialysis, CAD and aortic valve replacement, was admitted for confusion that started the morning of admission. CT head, basic labs and urine toxicology were non-revealing. EEG recordings were consistent with subclinical non-convulsive status epilepticus and the patient was admitted to the ICU. [...]

Case Presentation: A 22-year-old man with asthma and atopic dermatitis presented with a pustular rash on his face and neck.  The rash began the day of presentation and was not painful or pruritic.   Lesions spread to the right eyelid, which caused swelling but no visual disturbance.    His eczema symptoms were more severe during the preceding [...]

Case Presentation: A 35 year-old female with a past medical history significant for type 2 diabetes mellitus, polycystic ovarian syndrome and migraine headache presented with alteration of mental status for 2 weeks. Patient endorsed progressive, generalized fatigue with intermittent episodes of confusion, behavioral disturbance, hypersomnia and short-term memory loss. Vital signs on admission were significant [...]

Case Presentation: A 64 year-old male with a past medical history significant for COPD presented with fever, abdominal pain and rash. Patient endorsed fever and chills for 2 weeks prior to inpatient hospitalization.  Patient subsequently noted intermittent generalized abdominal pain associated with hematochezia.  Patient noted onset of bilateral lower extremity rash the day of hospital [...]

Case Presentation: A 38-year-old man with untreated hyperthyroidism presented with two-week history of progressively worsening weakness and dyspnea along with a six-month history of unintentional 38 pound weight loss, diarrhea, and palpitations.  Exam was notable for confusion, cachexia, diffuse thyromegaly, jugular venous distension, exophthalmos, thyroid bruit, bilateral rales, and tachycardia (HR to 150s).  A transthoracic [...]

Case Presentation: A 26 year-old Singaporean man with no past medical history presented with two weeks of fevers and abdominal pain. Five months prior to admission, the patient traveled to Singapore.  Two weeks prior to presentation, he had an episode of sharp, right-sided abdominal pain accompanied by emesis.  He continued to have intermittent fevers, chills, [...]

Case Presentation:    A previously healthy 73-year-old male from Delaware presented with a three-day history of generalized fatigue, confusion and high grade fever in mid January.  He was found down at home and on initial evaluation was febrile to 39.5° C, tachycardic, and tachypneic.  His cardiopulmonary and abdominal exams were unremarkable.  He was disoriented but [...]

Case Presentation: A 66-year-old male with history of type 1 Von Willebrand disease, colonic polyps, and gastric ulcer from naproxen use due to osteoarthritis presented with a 3-week history of lethargy and fatigue with walking short distances. He denied melena or hematemesis but did report consistent ibuprofen use for his osteoarthritis over the past few [...]