Background: Adverse events (AEs) after discharge occur in 19–28% of hospitalized patients.(1) Understanding whether patient-reported and clinical factors from the electronic health record (EHR) can predict post-discharge AEs is increasingly important given the growing population of hospitalized adults with multiple chronic conditions (MCC) being discharged home. This AHRQ-funded study aimed to develop an interoperable prediction [...]

Background: Delirium is a common clinical syndrome, particularly among elderly patients in the inpatient hospital setting, and carries considerable associated morbidity. These patients can display symptoms of inattention, agitation, and restlessness, often necessitating the use of chemical or physical restraints to ensure the safety of the patient and staff. Unfortunately, these interventions are not without [...]

Background: Diagnostic error may occur in up to 5% of all adult hospitalizations, leading to prolonged length of stay, higher cost, and significant morbidity and mortality. Improving diagnostic safety requires measurement, analysis, and learning accelerated by dissemination. While safety is at the forefront of hospital priorities, organizational readiness to address diagnostic safety lacks consistent deployment [...]

Background: Intravenous vancomycin treatment is often necessary beyond hospitalization. Peripherally inserted central catheters (PICCs) are usually placed for this indication. Whether the less invasive midline catheters (midlines) are safe alternatives for outpatient parenteral antimicrobial therapy (OPAT) with vancomycin is unclear. We compared the safety of midlines and PICCs among patients receiving vancomycin for OPAT. Methods: [...]

Background: Suicide attempt and self-injury (SA/SI) are frequent reasons for medical hospitalizations, yet little is known about length of stay (LOS) among youth hospitalized for SA/SI. LOS is commonly used to measure quality of patient care and resource use within hospitals, and a comprehensive understanding of factors associated with LOS among youth admitted for SA/SI [...]

Background: Mounting evidence supports the use of point-of-care ultrasound (POCUS) in medicine and pediatrics to improve outcomes, maximize patient safety, and increase patient satisfaction and success of procedures.The literature describes the utility of POCUS in several areas of pediatric care (the emergency department, pediatric and neonatal intensive care unit, and post-acute care setting), however, we [...]

Background: Pediatric Hospital Medicine (PHM) is one of the newest subspecialties and was recognized by the American Board of Medical Specialties in 2016, with its first fellowship programs accredited in 2020. While research barriers in academic medical practice have been identified in prior studies, the facilitators and barriers to research productivity for PHM faculty in [...]

Background: Caregivers of Children with Medical Complexity (CCMC) are essential to their child’s care during hospital admissions. Prior research suggests that prolonged hospitalization of their child negatively impacts the emotional, physical and psychosocial well-being of CCMC. However, there is a paucity of data regarding caregivers’ perspectives on potential effective solutions to improve their own wellness [...]

Background: Growth faltering (or failure to thrive) is a common paediatric problem, found in approximately 3-5% of hospitalized children1,2. Inpatient evaluation of growth faltering generally focuses on identifying the underlying etiology of poor weight gain, but complex genetic conditions can be difficult to identify during a short hospital admission. In a recent study that followed [...]

Background: Information about how genetic testing is used in the NICU and how it changes clinical management is limited. In addition, genetic testing strategies are rapidly evolving, and having a baseline understanding of our current testing strategies and their clinical utility is important. Among infants admitted to children’s hospitals NICU, about 10-30% have a congenital [...]