Background: Patients with end stage renal disease (ESRD) are at significantly increased risk for both thrombosis and bleeding relative to those with normal renal function, which makes anticoagulation particularly challenging. Evidence suggests that rivaroxaban and dabigatran are associated with a higher risk of bleeding in ESRD patients. To date, no large national cohort studies have [...]

Background: Arterial (3-fold) and venous (10-fold) thromboembolism are more common in myeloproliferative neoplasm (MPN) than general population with rates as high as 50% in polycythemia vera (PV) and essential thrombocythemia (ET).1,2 While primary prophylaxis with aspirin is not debated for prevention of arterial and venous thromboembolism, the choice of anticoagulant for secondary prophylaxis and treatment [...]

Case Presentation: A 78-year-old African American female with a history of coronary artery disease (CAD) with stent placement, hypertension, and hyperlipidemia developed chest pain after being admitted for pulmonary embolism secondary to recently diagnosed pancreatic cancer. She was treated appropriately, but developed severe chest pain on day six of her stay. The patient’s vital signs [...]