Background: Obesity is associated with many cardiopulmonary comorbidities independently associated with worse health outcomes in acute illness, yet the physiological mechanisms potentially making obese patients more susceptible to COVID-19 remain uncertain. Adiposity-derived immunosuppression, increased thrombogenic potential, and predilection towards inflammatory hyperreactivity have all been postulated as potential mediators of this phenomenon. Yet, the most obvious [...]

Background: Obesity is associated with overall higher mortality risk in the general population however, some authors have noted patterns to suggest a survival advantage in a certain clinical subpopulation. Obesity paradox is reported for stroke, myocardial infarction, heart failure, renal disease, and diabetes. Clostridium difficile infection (CDI) is the most common nosocomial infection in the [...]