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2020-05-20T12:01:36-05:00
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Search Results for
cUTI
Abstract Number: F16
CLINICAL STABILITY INDICATORS BETWEEN ERTAPENEM AND TEBIPENEM PIVOXIL, AN ORAL CARBAPENEM, IN HOSPITALIZED ADULTS WITH COMPLICATED URINARY TRACT INFECTION
SHM Converge 2022
Background: Treatment of complicated urinary tract infections (cUTI), including acute pyelonephritis (AP) due to multi-drug resistant (MDR) Gram-negative uropathogens (e.g., extended-spectrum ß-lactamase (ESBL)-producing and fluoroquinolone-resistant strains) is associated with poor outcomes and increase costs of care. In the setting of limited alternative oral options, patients with cUTI/AP are commonly hospitalized to receive intravenous (IV) antibiotic […]
Abstract Number: N17
ORAL TEBIPENEM PIVOXIL IS NON-INFERIOR TO IV ERTAPENEM IN COMPLICATED URINARY TRACT INFECTION (CUTI) AND ACUTE PYELONEPHRITIS (AP): ADAPT-PO STUDY
SHM Converge 2022
Background: Tebipenem pivoxil hydrobromide (TBP-PI-HBr) is an orally bioavailable prodrug that is rapidly converted in plasma to the carbapenem, tebipenem. Tebipenem has in vitro activity against select multidrug-resistant Gram-negative pathogens, including fluoroquinolone-resistant and extended-spectrum ß-lactamase (ESBL)-producing Enterobacterales. TBP-PI-HBr is being developed in the United States as the first oral carbapenem for treatment of cUTI and […]
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