Case Presentation: A 33-year-old woman with a past medical history of a calcaneal fracture requiring internal fixation complicated by poor wound healing and repair with a free flap, and polymicrobial osteomyelitis on home amoxicillin-clavulanate and IV daptomycin presented with three days of fevers, chills, and generalized malaise. She reported adherence to her home antibiotic regimen. […]