Case Presentation: A 36-year-old male with history of keratoconus, corneal scars following corneal transplant, asthma, eczema, chronic herpes simplex virus 1 (HSV-1) and varicella zoster virus (VZV), presented with concerns of eye involvement secondary to HSV-1 versus VZV reactivation. Physical examination revealed periorbital edema, vesicular lesions in trigeminal nerve ophthalmic distribution, neck and upper extremities. […]