Background: Diabetic Ketoacidosis (DKA) is the most common severe acute complication of diabetes, and has shown to be worsened by COVID-191. Several studies have found an association between COVID-19 and worsened outcomes from diabetic ketoacidosis (DKA).2 Vaccination against COVID-19 has led to substantial declines in the frequency, severity, and mortality from acute infection, but little […]

Background: The presence of concomitant diabetic ketoacidosis (DKA) with acute pancreatitis (AP) is not uncommon and is associated with unfavorable outcomes (1,2). However, the diagnosis of AP in DKA patients is often missed because of the overlapping clinical features. Data comparing clinical characteristics and outcomes of patients with co-existing DKA and AP with DKA alone […]

Background: Diabetic ketoacidosis (DKA) remains one of the commonest causes of medical and intensive care unit hospitalisations. DKA is a preventable hospital admission which is associated with multiple modifiable risk factors. However, little is known about factors that can predict healthcare resource utilisation in DKA. Previous studies have explored clinical and biochemical factors affecting the […]

Background: Diabetes mellitus (DM) is a chronic disease where treatment is directed toward reducing and delaying its potentially severe short- and long-term complications. The estimated population (20-79 years old) with diabetes is 32.22 million in the United States, and 12.5% of people live with undiagnosed diabetes (Figure 1). Diabetes Mellitus is currently the most prevalent […]

Case Presentation: A 44-year-old male hospitalized for an extended period with severe diarrhea and polyarthritis developed worsening anion gap metabolic acidosis (AGMA) over the course of 10 days. The patient was being treated for septic arthritis in the background of polyarticular gout with vancomycin, ceftriaxone, colchicine, indomethacin, and acetaminophen. Acetaminophen was dosed as needed on […]

Case Presentation: A 47-year-old female with a history significant for poorly controlled T1DM and hypothyroidism presented after being found unresponsive following episodes of vomiting for the past 24 hours. The patient was found to have DKA, high anion gap metabolic acidosis, and shock with blood pressure of 65/31. Labs showed blood glucose levels of 983, […]