Case Presentation: A 96-year-old male with a history of type 2 diabetes mellitus, hypertension, coronary artery disease, and recurrent skin malignancies (melanoma and squamous cell carcinoma) presented with acute epigastric abdominal pain radiating to the back accompanied by nausea and anorexia. He had two previous episodes of similar presentation at another healthcare facility. His recent [...]

Case Presentation: We report the case of a 45-year-old female with stage IA triple-negative breast cancer treated with neoadjuvant chemotherapy and pembrolizumab who developed secondary adrenal insufficiency due to adrenocorticotropic hormone (ACTH) deficiency six months after stopping the immune checkpoint inhibitor. She presented with persistent nausea, vomiting, weight loss, and altered mental status. Laboratory results [...]

Case Presentation: We present the case of a 77-year-old man admitted with failure to thrive and progressive dyspnea. He had a 6-year history of lung squamous cell carcinoma and a recent history of immune checkpoint inhibitor (ICI) toxicity (myocarditis, pneumonitis, and hepatitis), currently on week 27 of a prednisone taper (35 mg daily). He was [...]

Case Presentation: An 81-year-old man with a history of urothelial carcinoma treated 10 months ago with right radical cystoprostatectomy and nephroureterectomy with ileal conduit followed by seven cycles of adjuvant atezolizumab and tiragolumab, two immune checkpoint inhibitors (ICI), was admitted with malaise, anorexia, and fever for 2 months. His past medical history included left lung [...]