Case Presentation: A 38-year-old male with presumed seronegative rheumatoid arthritis (RA), irritable bowel syndrome with diarrhea (IBS-D), and reported Lyme disease (negative serology) presented with acute dyspnea, pleuritic chest pain, and chronic relapsing fevers. Initial treatment with broad-spectrum antibiotics failed, and he developed acute hypoxic respiratory failure, requiring transfer to the Medical Intensive Care Unit [...]

Case Presentation: A 25-year-old woman with autism, developmental delay, and seizure disorder presented with weakness, joint pain, and lethargy. Initial findings included pancytopenia, elevated inflammatory markers, and hyperferritinemia. She was diagnosed with hemophagocytic lymphohistiocytosis (HLH) secondary to adult-onset Still’s disease. Despite treatment with corticosteroids, anakinra, and tocilizumab, her condition worsened, necessitating ICU admission. Discussion: HLH [...]