Background: The overall incidence of Clostridium difficile infection (CDI) is higher among patients with inflammatory bowel disease (IBD). The nature of this disease association is unknown but likely involves an altered gut microbiome and impaired host immune responses. Studies on CDI in IBD patients have yielded variable and conflicting results on outcome measures such as [...]

Case Presentation: A 58 year-old Caucasian female presented with a history of painful lesions of the gluteal, perineal, and vulvar areas. These lesions had been progressive with worsening drainage and scar formation over the last decade. She was treated with multiple antibiotics and antifungals in the past without improvement. No lesions were seen in her axilla. [...]

Case Presentation: A 56 year-old woman with well-controlled peri-rectal Crohn’s disease on infliximab presented to the hospital for management of a 2.5 year history of painful, draining vulvar dermatitis that had been biopsied twice and showed lichen simplex chronicus. Prior therapies included topical steroids and multiple antibiotic courses without significant or sustained improvement. MRI to [...]

Case Presentation:  A 35 year-old Chinese male with a known history of Crohn’s disease was diagnosed in 2014 and treated with nine doses of infliximab. He had normalization of his colon on follow up colonoscopy, but without complete resolution of the patient’s symptoms.  He was started on azathioprine and his symptoms worsened. Repeat colonoscopy showed [...]