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Abstract Number: 350
HYPOHPHYSITIS AND ADRENAL INSUFFICIENCY SECONDARY TO IPILIMUMAB AND NIVOLUMAB: A NEARLY LIFE THREATENING SIDE EFFECT OF NOVEL IMMUNOTHERAPY AGENTS
Hospital Medicine 2017, May 1-4, 2017; Las Vegas, Nev.
Case Presentation: A 70 year old female with metastatic melanoma presented to the emergency department with fatigue and lethargy for one month. She had recently completed 6 cycles of Nivolumab and Ipilimumab and was currently receiving Nivolumab monotherapy. Over the past month, she had worsening fatigue associated with nausea and decreased appetite. Lab work one [...]
Abstract Number: 444
FULMINANT LIVER FAILURE CAUSED BY DUAL IMMUNOTHERAPY FOR MALIGNANT MELANOMA
Hospital Medicine 2017, May 1-4, 2017; Las Vegas, Nev.
Case Presentation: A 70 year old male with metastatic malignant melanoma on immunotherapy with nivolumab and ipilimumab was sent to the hospital by his oncologist for abdominal pain and elevated liver enzymes.  His labs were notable for AST 275, ALT 1138, alkaline phosphatase of 394 and total bilirubin of 3.94. This patient had no known [...]
Abstract Number: 580
PITUITARY GONE AWRY
Hospital Medicine 2017, May 1-4, 2017; Las Vegas, Nev.
Case Presentation: Our patient was a 58 year old male with a history of metastatic melanoma on nivolumab and ipilimumab who was directly admitted from clinic to the medicine service for increased lethargy and flu-like symptoms. The patient described a one week history of fevers/chills, headache, muscle ache, and malaise; as well as nausea, vomiting, [...]
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