Background: The overall incidence of Clostridium difficile infection (CDI) is higher among patients with inflammatory bowel disease (IBD). The nature of this disease association is unknown but likely involves an altered gut microbiome and impaired host immune responses. Studies on CDI in IBD patients have yielded variable and conflicting results on outcome measures such as [...]

Case Presentation: A 27 yo male with ulcerative colitis (UC) and childhood asthma presented with a dry cough, fever and weight loss for 6 weeks. One and a half years prior to admission, he was diagnosed with UC for which he was started on oral mesalamine 1.2 g/day. Prior to admission, he visited an outpatient [...]

Case Presentation: A 23-year-old female with a history of acne presented with abdominal pain and bloody diarrhea for 1 day. The pain was crampy in nature and located in her lower abdomen, without radiation or modifying factors.  She was passing frequent watery bowel movements with a small amount of blood. She denied any recent travel, [...]

Case Presentation: A 42 year old African American male with a recent diagnosis of Ulcerative Colitis (UC) presented with recurrent bloody diarrhea, abdominal pain, fevers, chills, weight loss and was admitted for management of a presumed UC flare. On a previous admission 2 months prior, he had been diagnosed with UC with a colonoscopy and [...]

Case Presentation: A previously healthy 19-year-old woman presented to the emergency department with one week of abdominal pain, bloody diarrhea, and fever. Two weeks prior, she reported a non-specific flu-like illness. On admission, she was febrile, tachycardic, and hypotensive. She had a toxic appearance and a firm, diffusely tender abdomen. She had no oropharyngeal, pulmonary, [...]

Case Presentation: A 62 year-old Caucasian male, with a 10-year history of ulcerative colitis (UC), presented to ER with acute onset of throbbing frontal headache for 1 day with associated photophobia and severe right eye pain. He reported having nausea and several episodes of vomiting. He denied any vision changes, speech difficulty, focal weakness, rash, [...]

Case Presentation: A 79-year-old male patient with a history significant for metastatic melanoma to the right axillary lymph node and recurrent diarrhea secondary to ipilimumab-induced colitis is admitted for uncontrolled diarrhea with rectal bleeding.  He has had several prior admissions for diarrhea, which have been successfully treated with IV steroids, but has recurrent diarrhea when [...]

Case Presentation: This is a 59 year-old woman with ulcerative colitis (UC) who initially presented with frequent episodes of bloody diarrhea and persistent abdominal pain for two months. The patient had been controlled for years on azathioprine and infliximab but was unable to continue infliximab several months prior to presentation. The patient began to complain [...]