Case Presentation: A 65-year-old black woman with history of longstanding controlled HIV on highly active antiretroviral therapy (HAART) and chronic Hepatitis C co-infection, presented with a 2-day history of worsening lower back pain. She was compliant with her HAART regimen (darunavir, lamivudine, raltegravir and ritonavir) since her diagnosis in 1994, with persistently undetectable viral loads [...]