Background: Results from the recent SPRINT trial demonstrate lower rates of fatal and non-fatal major cardiovascular events and all-cause mortality in non-diabetics at high cardiovascular risk with intensive versus standard treatment, i.e., less than 120 versus less than 140 mmHg systolic, respectively. However, the long-term outcomes remain unknown.Methods: A validated state-transition model with multivariate risk [...]

Case Presentation: A 65-year-old woman was admitted to our hospital because of episodes of altered mental status and high blood pressure. Forty days prior to admission, the patient was taken to the emergency department with an altered mental status and hypertension. Her blood pressure was 226/129 mmHg, while her blood glucose level was 48 mg/dL. [...]

Case Presentation: A 74-year-old female with a past medical history of chronic pulmonary emboli, left ventricular heart failure, and hypertension presented with shortness of breath on exertion and bilateral lower extremity edema for one week. On examination, she was found to have jugular venous distention, crackles in bilateral lung bases, and 3+ pitting peripheral edema. [...]

Case Presentation: An 80 year old lady presented with fever and confusion since 4 days. She denied any recent trauma, infection, dehydration, medication change, or nutrient deficiency. Her medical history was only significant for anxiety, for which she took alprazolam at home. On physical exam she appeared agitated and disoriented, with a heart rate of [...]