Case Presentation: 60-year-old gentleman with a history of autoimmune hemolytic anemia presented to emergency department with acute onset of severe left leg pain, edema, and cyanosis. On examination of his left leg, pulses were not palpable distal to posterior tibialis but motor functions remained intact. There were no blebs or bullae noted. He was requiring [...]

Case Presentation: A 17yo female with sickle cell disease (SCD; HbSS genotype) presented with pain crisis and acute chest syndrome. She was treated with appropriate antibiotics (ceftriaxone/cefdinir and azithromycin). During the first few days of her hospitalization, she required 2 pRBC transfusions for down trending hemoglobin (Hb) and low reticulocyte count. On hospital day 11, [...]