Background: Heparin-induced thrombocytopenia (HIT) syndrome is an immune-mediated disorder producing thrombocytopenia and thrombosis, with or without prior exposure to heparin. Although avoidance of heparin products and non-heparin anticoagulants are used, immune-based therapies including intravenous immunoglobulin have been tried when the thrombocytopenia persists or there is breakthrough thrombosis. We sought to systematically review and analyze the […]

Case Presentation: 66 year old man with a history of eosinophilic granulomastosis with polyangiitis presented with ascending numbness and unsteadiness that worsened over two days and finally manifested as paraesthesia and weakness in all extremities, gait imbalance, and diplopia. Three weeks prior to presentation, the patient had received the flu vaccine. Neurology was consulted upon […]

Case Presentation: A 27 y.o. male with a history of pre-B cell ALL in complete remission on maintenance therapy with vincristine, 6-mercaptopurine, methotrexate, and receiving intrathecal methotrexate for CNS prophylaxis presented with a 2 week history of fevers, productive cough, night sweats, and fatigue. He had no recent exposure to children or sick contacts. Physical […]

Case Presentation: West Nile (WN) virus, a member of the Japanese encephalitis virus antigenic complex, is the leading cause of mosquito-borne disease in the continental United States. Approximately 1 out of 250 patients develop neuroinvasive disease including encephalitis, meningitis, acute flaccid paralysis and opsoclonus-myoclonus syndrome (OMS). Sparse data exist regarding potential treatments for WN virus […]