Background: Pneumocystis jirovecii pneumonia (PJP) is an opportunistic infection associated with lymphopenic conditions including HIV/AIDS, hematologic malignancy1, organ transplantation2, and lymphocyte-suppressive therapies such as high dose glucocorticoids3,4. PJP prophylaxis, which is highly effective, is indicated when the incidence of PJP exceeds the rate of adverse events due to prophylaxis.4,7 Guidelines from the American Thoracic Society [...]

Case Presentation: A 50-year-old female was admitted with shortness of breath, cough and fevers. Her past medical history was significant for breast cancer undergoing active neoadjuvant chemotherapy with doxorubicin and cyclophosphamide. She was hypoxic requiring 2L of oxygen via nasal cannula and febrile to 39.0°C. Labs revealed a WBC of 12.0 x 109/L (4.5-11.0 x [...]