Case Presentation: A 36-year-old male with a history of B-cell acute lymphoblastic leukemia (ALL) treated with Hyper-CVAD with intrathecal chemotherapy and allogenic hematopoietic stem cell transplant (HSCT) from a haploidentical donor (CMV D-/R+). His ALL relapsed 8 months after transplant and he subsequently underwent pre-phase chemotherapy for future CAR T-cell therapy, developing pancytopenia. He was [...]

Case Presentation: An 18 year old male with no past medical history presented with one month history of nausea and vomiting, 10 pound weight loss, and abdominal pain. Vital signs were normal and physical exam only remarkable for mild tenderness to palpation in the right upper quadrant. Admission labs were notable for leukocytosis (WBC 14) [...]

Case Presentation: A 59 year old man with no past history presented with continuous gingival bleeding for 3 days. He underwent dental cleaning and tooth extraction 3 days prior and since then had been having bleeding from the extraction site associated with headache and dizziness. On presentation blood pressure 110/70mmHg, pulse 105/min, temperature 98F, respiratory [...]

Case Presentation: A 27 y.o. male with a history of pre-B cell ALL in complete remission on maintenance therapy with vincristine, 6-mercaptopurine, methotrexate, and receiving intrathecal methotrexate for CNS prophylaxis presented with a 2 week history of fevers, productive cough, night sweats, and fatigue. He had no recent exposure to children or sick contacts. Physical [...]

Case Presentation: A twenty-year-old female with acute lymphoblastic leukemia presented to the ED with one day of fever and a non-productive cough. Her vitals were significant for a fever of 102.8 F. Lung auscultation revealed diminished air entry to the right lower lung field. The rest of her physical exam was unremarkable.Chest radiograph demonstrated a [...]

Case Presentation: We present a case series of three patients who developed secondary B-cell acute lymphoblastic leukemia (B-ALL) after multiple myeloma (MM) treatment. Case 1: A 71-year-old male with a four-year history of standard-risk kappa MM presented with weakness, fever, cough, and pancytopenia. His MM had initially been treated with six cycles of lenalidomide (R), [...]