Background: Prophylactic anticoagulation is effective at reducing the risk of venous thromboembolism (VTE), but can also increase the risk of bleeding. Whether anticoagulant prophylaxis should be modified for underweight patients to minimize bleeding complications is unknown.  We sought to determine whether being underweight is associated with the risk of major bleeding in hospitalized medical patients [...]

Background: Obstructive sleep apnea (OSA) is closely associated with obesity, and weight reduction is a critical component of its management. Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) agonists have shown promise in promoting weight loss, potentially improving outcomes in OSA patients. We aimed to calculate the mean reduction in BMI and waist circumference after [...]

Case Presentation: A 28-year-old, 447 lb man with hypothyroidism and depression was hospitalized for neurosurgical intervention for severe lumbar spinal stenosis. He had one risk factor from the Revised Cardiac Risk Index due to the spinal procedure, and his EKG, echocardiogram, and renal function were normal. He had no history of diabetes, TIA/CVA, or cardiac [...]