Case Presentation: A 56-year-old Caucasian male with no pertinent medical history presented with 4 months of progressive left lower extremity weakness, gait instability, headache, and an 8-lb weight loss. Physical exam was notable for left leg spasticity, positive left Babinski sign, and asymmetric dysmetria on heel to shin on his left compared to his right [...]

Case Presentation: The World Health Organization designates a rare disease as one affecting under 6.5-10 per 10,000 people (1). We present a case of disparate findings, ultimately diagnosing Erdheim-Chester Disease (ECD), a rare non-Langerhans histiocytic multisystem disorder with fewer than 1000 reported cases (2,3).A 63-year-old man presented with months of progressively worsening anasarca, acute on [...]

Case Presentation: A 61 year-old-female presented to an outside institution with worsening exertional dyspnea, chest pressure, and fatigue. Echocardiogram revealed a large pericardial effusion bordering on tamponade which was drained with great improvement of symptoms. CT Chest/Abdomen/Pelvis revealed perirenal soft tissue invasion, which was biopsied. Patient was then referred to our institution for further management; [...]