Background: Hydroxyurea is an FDA approved medication for use in adults with sickle cell disease. Clinical guidelines, based on high quality evidence, recommend its use in all adults with sickle cell anemia and 3 or more moderate to severe pain crises within one year.  Studies suggest its use to be inappropriately low. We assessed local [...]

Case Presentation: A 75 year old Caucasian woman, previously diagnosed ET and atrial fibrillation, presented to emergency room with acute on chronic shortness of breath. Her dyspnea was earlier attributed to chronic bronchitis in the absence of evidence of any other pathology. However, this time she had bilateral coarse crackles which correlated with her chest [...]

Case Presentation: Adverse drug reactions are any injury that is a result of medication use and can be classified into two categories. Type A are reactions that are common and predictable. Type B are reactions that are rare and unpredictable. An 81-year-old woman with history of essential thrombocythemia presented with an intermittent, relapsing and remitting [...]

Case Presentation: An 84-year-old Caucasian male presented to the emergency department with a chief complaint of fevers, rigors and altered mental status. On physical exam, the patient was a well-nourished, well-developed male with a fever of 102F. His chest x-ray was clear and free of any infiltrates. His urinalysis was benign with only trace proteins [...]