Background: Prolongation of the QT interval is associated with adverse cardiac events, mainly a distinctive ventricular tachycardia known as Torsades de Pointes. Prolonged QT can be congenital or acquired and is OFTEN measured as a corrected QT interval of >450 msec for men and >470 msec for women. In a world where medical knowledge and [...]

Case Presentation: A 35-year-old female presented to the emergency department after an episode of syncope. She takes methadone (180 mg/day) for opioid dependency. She had a recent relapse and returned to illicit drug use after a period of sobriety. Vital signs were notable for tachycardia, blood pressure and respiratory rate were normal. On physical exam [...]

Case Presentation: A 57-year-old male with past medical history of alcohol-induced chronic pancreatitis complicated by chronic pain, opioid use disorder (OUD) on methadone, and depression on sertraline presented to the emergency department with dizziness, dyspnea, and nausea. About six months prior to admission, he had been transitioned from buprenorphine to methadone for better pain control. [...]

Case Presentation: A 25-year-old female with no significant medical history presented with recurrent syncope, reporting no use of medications, stimulants, alcohol, or illicit drugs, and no family history of cardiomyopathies or sudden cardiac death. Her first syncopal episode in December 2020 occurred suddenly, without prodromal symptoms, followed by two more episodes in 2021 and 2022, [...]

Case Presentation: A 44-year-old female with severe opioid use disorder (OUD) was admitted after a benzodiazepine withdrawal seizure. Her history was significant for methadone 165 mg daily dosing, anxiety managed with daily unprescribed benzodiazepines, and alcohol use disorder in remission. She had a prolonged QT interval, with a notable episode 18 months prior, when she [...]