Case Presentation: A 70 year old female with metastatic melanoma presented to the emergency department with fatigue and lethargy for one month. She had recently completed 6 cycles of Nivolumab and Ipilimumab and was currently receiving Nivolumab monotherapy. Over the past month, she had worsening fatigue associated with nausea and decreased appetite. Lab work one [...]

Case Presentation: A 79-year-old male patient with a history significant for metastatic melanoma to the right axillary lymph node and recurrent diarrhea secondary to ipilimumab-induced colitis is admitted for uncontrolled diarrhea with rectal bleeding.  He has had several prior admissions for diarrhea, which have been successfully treated with IV steroids, but has recurrent diarrhea when [...]

Case Presentation: A 66 year old female with a past medical history significant for metastatic melanoma undergoing immunotherapy with ipilimumab (treatment start date three weeks prior) and nivolumab, poorly controlled T2DM, abnormal liver function tests, and hyperlipidemia who initially presented to an urgent care, presents to the emergency department with double vision and difficulty swallowing. [...]