Case Presentation: An 82-year-old male with a history of coronary artery disease, type 2 diabetes mellitus, and cholangiocarcinoma presented with palpitations. Elevated troponin levels were noted at an outside hospital, he left against medical advice and present to UCLA for further evaluation. He presented with fatigue since his recent first cycle of treatment (cisplatin, gemcitabine, [...]

Case Presentation: This case investigates the etiology of acute interstitial nephritis (AIN) in a metastatic melanoma patient who was transitioned from immune-checkpoint inhibitors (ICIs) to targeted BRAF-MEK inhibitors (BRAFi/MEKi). A 73-year-old man with cutaneous melanoma with lung metastases presented to the emergency room for generalized weakness, fevers, and renal failure. Six weeks prior to his [...]

Case Presentation: An 83-year-old male with a history of seizures, CHF, hyperlipidemia, obstructive sleep apnea, and BPH presented with 2-3 days of altered mental status. His family reported worsening leg swelling and blisters for the past few months, with a rash spreading to his upper extremities and wounds draining serosanguinous fluid. He was hypoxic in [...]

Case Presentation: We present a case of early and atypical checkpoint inhibitor pneumonitis (CIP) in an elderly female with chronic obstructive pulmonary disease (COPD) who received just two infusions of Pembrolizumab for stage III non-small cell lung carcinoma (NSCLC). Before starting immunotherapy, she had been receiving chemotherapy with carboplatin and paclitaxel for 6 months. The [...]

Case Presentation: A 64-year-old female with eosinophilic pneumonia, eosinophilic myocarditis, and hypothyroidism presented to the ED with four days of left upper extremity weakness. Symptoms began with a “sensation of heat,” progressing to left-sided weakness, impaired motor coordination, and fecal incontinence. She denied dizziness, visual changes, chest symptoms, falls, or head trauma.She previously used corticosteroids [...]