Case Presentation: A 63-year-old man with a history of atopy recently started on dupilumab presented to a hospital in Central Appalachia with 1-week of flu-like symptoms, rigors, and right upper abdomen pain. He was hypoxic with SpO2 75% on room air, febrile to 103.3°F, tachycardic to 105 bpm. He was placed on 2 L nasal [...]