Case Presentation: An 81-year-old man with a history of urothelial carcinoma treated 10 months ago with right radical cystoprostatectomy and nephroureterectomy with ileal conduit followed by seven cycles of adjuvant atezolizumab and tiragolumab, two immune checkpoint inhibitors (ICI), was admitted with malaise, anorexia, and fever for 2 months. His past medical history included left lung [...]