Case Presentation: A 71-year-old man presented with 1 week of progressive fatigue and weakness. Upon arrival, he stated that he could not get out of bed, even to use the bathroom. Notably, he had undergone an infusion of carboplatin, pemetrexed, and pembrolizumab for treatment of lung adenocarcinoma 9 days before presenting. He attributed his symptoms [...]

Case Presentation: Tumor lysis syndrome (TLS) is a potentially fatal complication usually seen in rapidly proliferating and chemo-sensitive malignancies like acute leukemia and lymphomas. (1-3) It is termed “spontaneous” (STLS) when TLS occurs without prior chemotherapy. (1) The incidence of STLS in solid tumors is infrequent/rare and can be fatal without early recognition and aggressive [...]