Background: Among patients undergoing cardiac surgery on cardiopulmonary bypass (CPB), post-operative complications are common, occurring in up to 67% of patients, and significantly impact long-term outcomes. We conducted a Phase 2 clinical trial of RBT-1, a pharmacologic preconditioning drug, to assess cytoprotective biomarkers and clinical outcomes. Herein, we report our final results. Methods: This randomized, [...]

Case Presentation: We present the case of a 64-year-old male with a history of pulmonary embolism status post IVC filter, and recent viral constrictive pericarditis with exudative pericardial effusion requiring pericardiocentesis and bilateral pleural effusions requiring chest tubes, who was admitted for dyspnea, cyanosis, and confusion. Vitals were blood pressure 78/51, heart rate 60, respiratory [...]