Background:

Admission hyperglycemia has been associated with adverse clinical outcomes of patients admitted with acute myocardial infarction, stroke, or trauma. The effect of admission or discharge glucose level on clinical outcomes, particularly readmissions in ADHF, is less clear.

Methods:

We performed a careful chart review of 332 patients consecutively admitted for ADHF between 2004 and 2005, including glucose values at admission and at discharge.

Results:

In our study cohort (mean age 66 ± 15 years, 40% male, 22% LVEF > 50%, 44% diabetic), the overall 30‐day mortality and 30‐day readmission rates were 1.5% and 15.36%, respectively.

Overall, a trend toward an increased readmission rate was noted for the patients whose discharge glucose level was in the highest quartile, but the results did not reach statistical significance. No relationship was observed between admission glucose level and readmission. Readmission rate did not vary by patient diabetes status for both admission and discharge glucose levels (see the table). On the contrary, patients whose admission glucose level was in the first quartile appeared to be at higher risk of 30‐day and 60‐day mortality (odds ratio [OR] = 4.55 [0.7527.75] and 3.62 [1.27‐10.32]), although these observations were limited by small event rates.

Conclusions:

In our ADHF cohort, there was a trend toward a higher discharge glucose level and a higher 30‐day rehospitalization rate. Admission glucose level did not appear to correlate with readmission rate in our study. A larger sample size may bear out relationships of admission and discharge glucose levels with ADHF mortality or with readmissions that may not be currently evident.

Author Disclosure:

A. Aneja, None; W. H. Fares, None; R. Kaw, None; A. Paneerselvam, None; A. Rajamanickam, None; A. Usmani, None; V. Dimov, None; W. W. Tang, None.