Background: Stroke is one of the most common causes of adult mortality. With changes in lifestyle, the increase in risk factors is leading to an increase in the number of cases. Mean platelet volume (MPV) is associated with an increase in platelet size and hence increased production of pro-inflammatory cytokines and increased expression of platelet [...]

Background: Diabetic ketoacidosis (DKA) remains one of the commonest causes of medical and intensive care unit hospitalisations. DKA is a preventable hospital admission which is associated with multiple modifiable risk factors. However, little is known about factors that can predict healthcare resource utilisation in DKA. Previous studies have explored clinical and biochemical factors affecting the [...]

Background: Approximately one-third of patients with acute ischemic stroke (AIS) develop hyperglycemia regardless of pre-existing history of diabetes [1]. Hyperglycemia is associated with increased risk of hemorrhagic transformation and can be considered as a predictor of poor functional outcome after intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) [2]. Additionally, risk of death, hemorrhagic complications, and [...]

Background: Recent work by the authors showed that over half of the incidences of hypoglycemia in hospitalized diabetics involved patients with CKD, and that 18% of patients with diabetes and end-stage renal disease (ESRD) had a hypoglycemic episode while hospitalized. The importance of reducing inpatient hypoglycemia is reflected in the Centers for Medicare and Medicaid [...]

Background: Admitted patients with Type II Diabetes Mellitus (T2DM) are often placed on sliding scale insulin with four fingerstick blood glucose (FSBG) tests per day, regardless of home insulin use or baseline glycemic control. FSBG testing in the inpatient setting allows for real-time insulin adjustment to protect patients from significant hypo- or hyperglycemia, but FSBG [...]