Background: Syphilis cases in the United States increased by 28.6% between 2020 and 2021. San Francisco was the highest-risk county for early syphilis in 2017, and between 2017 and 2021, syphilis diagnoses further increased by 12%, with a 200% increase in syphilis cases among women and a 333% increase in congenital syphilis cases compared to [...]