Background: Acute heart failure exacerbations are a leading cause of morbidity and mortality, with high rates of hospitalization and healthcare expenditure. Guideline-directed medical therapy (GDMT) has improved outcomes in heart failure with reduced ejection fraction (HFrEF), improved ejection fraction (HFimpEF), preserved ejection fraction (HFpEF), and moderately reduced ejection fraction (HFmrEF). Recent studies highlight the benefits [...]

Background: In the U.S., hospitalizations related to Congestive Heart Failure (CHF) are amongst the most frequent and costly, yet a unified approach toward improving outcomes remains elusive. In 2022, the AHA/ACC/HFSA released updated guidelines for the management of heart failure. Recommendations include prescribing four classes of medications for eligible patients, known as guideline-directed medical therapy [...]