Background: Over 32 million patients in the United States have a penicillin (PCN) allergy label in their medical chart.1 Studies have demonstrated that 15-20% of hospitalized patients are labeled PCN allergic. However, IgE-mediated PCN allergy wanes over time and up to 80% of patients with a listed PCN allergy can tolerate PCN after 10 years. [...]

Background: Penicillin is the most commonly documented drug “allergy” on hospital admission. Patients with listed penicillin allergies have higher rates of treatment failures, antibiotic resistance, and average length of stay. This has downstream implications impacting healthcare utilization, infection prevalence, and cost. However, the majority of these reported allergies are inaccurate, and over 90% of these [...]

Case Presentation: A 76-year-old woman presented to the hospital with complaints of dyspnea and bilateral lower extremity edema. She had a past medical history of chronic kidney disease (CKD) stage 4 and inflammatory bowel disease with ileostomy and reported allergy to infliximab. IV furosemide was started for acute congestive heart failure. CTA chest was done [...]

Case Presentation: 68-year-old male with a history of recurrent angioedema, complicated by intubation, presented to the emergency room (ER) for progressive tongue swelling and dyspnea prior to arrival. He was on aspirin 81 mg for years with a recent addition of cilostazol for peripheral artery disease. Physical exam was significant for tongue and lip swelling. [...]