Case Presentation: Patient is a 74-year-old male with type 2 diabetes complicated by neuropathy, lumbar spinal stenosis with radiculopathy, and venous insufficiency who presented to the ED for evaluation of several months of waxing and waning bilateral lower extremity weakness with progression of symptoms causing multiple falls. Initial CT head revealed an 11 mm acute [...]

Case Presentation: A 96-year-old male with a history of type 2 diabetes mellitus, hypertension, coronary artery disease, and recurrent skin malignancies (melanoma and squamous cell carcinoma) presented with acute epigastric abdominal pain radiating to the back accompanied by nausea and anorexia. He had two previous episodes of similar presentation at another healthcare facility. His recent [...]

Case Presentation: This case investigates the etiology of acute interstitial nephritis (AIN) in a metastatic melanoma patient who was transitioned from immune-checkpoint inhibitors (ICIs) to targeted BRAF-MEK inhibitors (BRAFi/MEKi). A 73-year-old man with cutaneous melanoma with lung metastases presented to the emergency room for generalized weakness, fevers, and renal failure. Six weeks prior to his [...]

Case Presentation: A 70-year-old man treated with Nivolumab for metastatic melanoma, presented with mild nausea and vomiting for a few days. He denied a change in urine output or appearance of urine, flank pain, or difficulty urinating. Creatinine on admission was 8.9 mg/dl (baseline 0.8mg/dl). Urinalysis revealed mild proteinuria, 21-50 WBCs/hpf. Spot protein/creatinine ratio was [...]