Background: Murine typhus, a flea-borne rickettsial disease traditionally found in warm, humid climates, is increasingly reported in non-endemic regions due to factors such as climate change and urbanization. Characterized by nonspecific symptoms including fever, headache, rash, and elevated liver enzymes, murine typhus often mimics common febrile illnesses such as influenza, viral exanthems, or sepsis. Delays [...]

Case Presentation: A 27-year-old male presented to the hospital after developing jaundice with elevated transaminases on routine labs. Patient described preceding two-week febrile illness characterized by general malaise, chills, and myalgias. He received two courses of antibiotics without resolution of symptoms. To manage fever, he consumed 7 grams/day of acetaminophen consecutively for 5 days. His [...]