Case Presentation: Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder that can involve multiple organs, including the central nervous system (CNS). Neuropsychiatric systemic lupus erythematosus (NPSLE) refers to a spectrum of neurological and psychiatric symptoms such as cognitive dysfunction, psychosis, mood disorders, and seizures. Status epilepticus is a rare and severe presentation often associated [...]

Case Presentation: A 32-year-old woman presented with progressively worsening abdominal distention for weeks associated with abdominal pain, postprandial nausea and emesis. The physical exam was notable for generalized tenderness and fluid wave. Lab work revealed proteinuria, acute kidney injury, normocytic anemia, and leukocytosis. She had undergone a diagnostic paracentesis at an outside hospital that had [...]

Case Presentation: A 37-year-old female with systemic lupus erythematosus (SLE), noncompliant with mycophenolate mofetil (MMF) and hydroxychloroquine, complicated by Class V membranous lupus nephritis and cirrhosis due to autoimmune hepatitis, presented with generalized weakness and altered mentation. This followed a recent admission for methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia and acute kidney failure requiring hemodialysis (HD), [...]

Case Presentation: A 48-year-old woman with a history of fibromyalgia presented with a three-month history of progressive dyspnea, muscle weakness, weight loss (20 kg), and worsening respiratory symptoms. She initially sought care for productive cough, fever, and dyspnea, receiving treatment for pneumonia with ceftriaxone on two occasions with transient symptom relief. However, her symptoms recurred [...]

Case Presentation: A 52-year-old female with discoid lupus on immunosuppressive medications and a history of gout presented with acute right wrist pain and swelling and subjective fevers. There was no history of trauma or other joint involvement. Notable examination findings include significant swelling of the right wrist without overlying erythema or induration. She was noted [...]

Case Presentation: A 26-year-old female with a past medical history of idiopathic thrombocytopenic purpura (ITP) presented to the hospital with a two-month history of progressive abdominal distension and nausea. On physical examination, she had decreased breath sounds at the bilateral lung bases and massive ascites. Laboratory tests revealed normocytic anemia, mild hyponatremia, slightly elevated creatinine [...]

Case Presentation: A 27 year old woman with systemic lupus erythematosus (SLE) and history of a single seizure episode presented with acute altered mental status. The patient was initially disoriented and nonverbal, able to open eyes but unable to track, intermittently responding to commands, and later deteriorating, becoming obtunded and eventually comatose. Her NIH Stroke [...]