Background: In the management of transplant-ineligible multiple myeloma (MM), therapeutic strategies are crucial for improving patient outcomes. Recent clinical trials have explored the efficacy of triplet vs dual therapy in this context. This meta-analysis aimed to evaluate the comparative effectiveness (overall survival [OS], progression-free survival [PFS], minimal residual disease [MRD] negative, and response rate [RR]) [...]

Case Presentation: A 48-year-old man with end-stage renal disease due to IgA nephropathy underwent a deceased donor kidney transplant in 2008, which resulted in graft failure. A second transplant in 2019 required additional thymoglobulin due to high panel reactive antibodies and was complicated by BK nephritis, treated with leflunomide. Since treatment, he had persistent leukopenia, [...]

Case Presentation: A 33-year-old man with end-stage renal disease status post renal transplant was readmitted to the hospital with recurrent acute kidney injury (AKI).During his first admission, he reported a few weeks of nonproductive cough, dyspnea, congestion, chills, and recent nausea with vomiting. He was afebrile with normal vital signs and normal SpO2. Respiratory panel [...]

Case Presentation: A 33-year-old female with a renal transplant 18 months prior was transferred to our hospital with acute kidney injury after presenting with acute gastrointestinal symptoms. One year earlier, a biopsy of the transplanted kidney revealed budding yeast consistent with Histoplasma capsulatum. Histoplasma urine and serum antigens were negative, and Itraconazole was discontinued after [...]

Case Presentation: A 63-year-old male with a past medical history of type 2 diabetes mellitus, paroxysmal atrial fibrillation, ESRD on HD, and acute myeloblastic leukemia (AML) (diagnosed in 2015) in remission s/p allogeneic MRD PBSCT (4/16) was admitted for generalized weakness and confusion. His hospitalization was complicated by worsening pancytopenia (Hgb 7.8 g/dL, WBC 3.2 [...]

Case Presentation: A 17-year-old female presented with a one-month history of persistent dry cough, worsened by lying flat, requiring multiple pillows to sleep comfortably. Initially treated for presumed pharyngitis, her symptoms persisted, prompting further evaluation. Echocardiography revealed a large pericardial effusion with a normal ejection fraction, leading to hospital admission. Imaging studies identified a 3.5 [...]

Case Presentation: A 25-year-old African American male with a history of Frasier syndrome, renal transplant, bilateral orchiectomy, and chronic immunosuppression presented to an outside hospital with a three-day history of shortness of breath and malaise. Workup revealed bilateral multifocal pneumonia and an acute kidney injury. He was transferred to the ICU at our hospital so [...]