Background: Prophylactic anticoagulation is effective at reducing the risk of venous thromboembolism (VTE), but can also increase the risk of bleeding. Whether anticoagulant prophylaxis should be modified for underweight patients to minimize bleeding complications is unknown.  We sought to determine whether being underweight is associated with the risk of major bleeding in hospitalized medical patients [...]

Case Presentation: A 94-year-old Female with chronic kidney disease (stage 4), recurrent urinary tract infections (UTIs), and hypertension presented with a 3 day history of worsening general weakness, left thigh soreness, and a left thigh hematoma which was noted by the home health aide. The patient had a hospitalization 1 month prior in which she [...]

Case Presentation: A 65-year-old male underwent vascular repair for a psuedoaneurysm of left brachiocephalic arteriovenous fistula. During surgery he was noted to have excessive bleeding and also postoperatively, he continued to ooze from the surgical site. His labs revealed PT of 33.5 seconds, INR of 3.3, and PTT of 53.7 seconds. His mixing studies showed [...]