Meeting
Abstract Number: 173
Hospital Medicine 2018; April 8-11; Orlando, Fla.
Background: Warfarin is commonly used in long-term anticoagulation and has a narrow therapeutic index. Dosing is dependent on intrinsic patient variables including cytochrome P450 2C9 (CYP2C9) and VKORC1 polymorphisms. High protein binding and CYP-dependent clearance mechanisms of NSAIDs also affect warfarin serum levels. This study investigates the observed pharmacologic interaction of concurrent NSAID and warfarin […]
Abstract Number: 648
Hospital Medicine 2018; April 8-11; Orlando, Fla.
Case Presentation: 52-year-old female with history of Stage IIIA triple negative right sided breast cancer, seizure disorder, and s/p lumpectomy presents with ataxia, confusion, and dyskinesia over the past 2 weeks. The patient is chronically on phenytoin, ondansetron, paroxetine, and potassium supplements. She has been on phenytoin since her last seizure three years ago. She […]