Background: Syncope scores San Francisco Syncope Rule (SFSR) and Evaluation of Guidelines in Syncope Study (EGSYS)(1) are used as screening tools for predicting adverse outcomes among patient with syncope(1, 2). Surprisingly for scoring systems used for risk stratification of same clinical condition, differ significantly based on variables of importance used in calculating individual scores. An [...]

Background: In an effort to improve the design of future noninferiority studies, the endpoints for registrational trials of antimicrobials for the treatment of community-acquired bacterial pneumonia (CABP) were recently updated [1]. Lefamulin (LEF) is a first-in-class systemic pleuromutilin antibiotic newly approved for the treatment of adults with CABP [2]. The efficacy of LEF was demonstrated [...]