Case Presentation: A 57‐year‐old woman who had undergone an elective total knee replacement 9 days earlier presented to the ED with 1 day of progressive, diffuse abdominal pain, nausea, and fevers. Her postoperative course had been notable only for a supratherapeutic INR of 6.2 in the setting of routine DVT prophylaxis with warfarin, for which […]

Background: Until the advent of novel oral anticoagulants (NOACs), Warfarin was the only oral agent available for the treatment of deep venous thrombosis (DVT) and Pulmonary embolism (PE). Bridging with parenteral anticoagulation until warfarin reaches a full therapeutic level often results in prolonged hospitalization. Rivaroxaban, Dabigatran, Apixaban, Edoxaban were approved by the FDA for DVT […]

Case Presentation: A 67‐year‐old man with a past medical history of hypertension and retroperitoneal mass presented to the emergency department followed the sudden onset of severe low back pain. He described it as non‐radiating, diffuse, and constant. He denied chest pain or headache. Five years earlier he had been admitted to the hospital for evaluation […]

Case Presentation: A 59-year-old man with a history of a chronic provoked bilateral pulmonary embolism with left lower extremity deep vein thrombosis (DVT), Non-ST-elevation myocardial infarction and hypercholesterolemia presented to the emergency department with acute, severe, constant left calf pain and swelling, exacerbated by standing. He stated that “I think I have another blood clot […]