Background: Pulmonary arterial hypertension (PAH) is a progressively debilitating disorder characterized by sustained increases in pulmonary vascular resistance and pulmonary arterial pressure, which eventually leads to right-sided heart failure. Current therapies for PAH work predominately as vasodilators to target symptoms, rather than focusing on the initial signals that promote disease progression. These therapies have proved […]

Case Presentation: A 44 year old woman with a history of Roux-En-Y gastric bypass (RYGB), hypothyroidism, and morbid obesity, presented with one day of confusion and somnolence. In the emergency department, she was unresponsive to voice with an initial Glasgow Coma Score of 9. Her temperature was 94 F, pulse 94 beats per minute, blood […]