Background: Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) are commonly-used antihypertensives which, despite renoprotective properties, can contribute to acute kidney injury (AKI)(1). Iodinated contrast media may also precipitate AKI, namely contrast-induced nephropathy (CIN), which has been associated with adverse patient outcomes(1–3). ACE inhibitors and ARBs are often held in the setting of iodinated [...]

Background: Sickle cell disease (SCD) is an autosomal recessive disease resulting in a broad range of functional and structural renal and cardiac alterations. Chronic kidney disease is with associated proteinuria, microalbuminuria and hemoglobinuria. Cardiac complications include diastolic heart disease, dysrhythmia and sudden death. In patients with advancing age, cardio-renal dysfunction can have substantial effects on [...]

Case Presentation: An 86-year-old female with history of hypertension and endometrial cancer was admitted for acute kidney injury. On presentation, patient’s creatinine was 3.06 mg/dL, associated with a dipstick urinalysis showing proteins 100 mg/dL. She was unresponsive to intravenous fluids, demonstrated by a persistent rise in her creatinine to 3.89 mg/dL. Urine output and oral [...]