Case Presentation: A 62 year-old man presented to the emergency room with recurrent, colicky generalized abdominal pain. He had presented with similar abdominal pain in the preceding 6 weeks, requiring two hospital admissions. Admissions were accompanied by asymmetric lower limb swelling and pain on one admission, and swelling of lips on this admission. Six weeks [...]

Case Presentation: A 61 years old male patient not known to have any medical problem presented to the emergency department after he noticed swelling in his mouth which increased in size to involve both lips, he reported loose bowel movements in the last couple weeks and mild arthralgia. His physical examination was completely normal apart [...]

Case Presentation: A 57 year old man with a history of heart failure with preserved ejection fraction (HFpEF), chronic kidney disease (CKD) and hypertension presented with two weeks of exertional dyspnea and lower extremity edema, followed by 4-days of progressive tongue swelling. One-month prior, he was initiated on an ACE inhibitor (ACEi) and experienced tongue [...]

Case Presentation: A 65 year old male with a history of diabetes mellitus type II complicated by neuropathy presented with profound facial and oropharyngeal edema after ingesting his usual medications. He was hemodynamically stable and without urticaria on exam. The patient could not speak and his airway was deemed compromised, so he underwent urgent nasopharyngeal [...]

Case Presentation: A 42-year-old African-American G8P5 woman with no significant past medical history developed tongue swelling the day after a preterm labor induction due to hydrops fetalis. The swelling initially resolved on the same day and the patient was discharged. However, during the following weeks, her tongue swelled almost every day. By the seventh week, [...]

Case Presentation: A 68-year-old Spanish speaking female with a history of chronic lymphocytic leukemia (CLL), in remission, and autoimmune hemolytic anemia (AIHA) presented to the ED with left sided neck pain, edema, and hoarseness. These symptoms had been present for the past four months despite three courses of antibiotics. Steroids given in the ED improved [...]

Case Presentation: A 23 year-old Guatemalan man presented to the hospital with right sided facial swelling, vesicular lesions on the eyelids and ulcers on the tongue. He was admitted with seven similar episodes during the past three months and was treated with steroids, antibiotics, antihistamines and also antiviral therapy for possible cellulitis and Herpes associated [...]

Case Presentation: A 21 year old Caucasian female with an unremarkable medical history presented with sudden onset of throat, lip and tongue angioedema. Due to concern for complications, she was given intravenous (IV) diphenhydramine, solumedrol and epinephrine (0.3mg of 1:1000 concentration). Patient developed acute hypoxic respiratory failure and hypotension. She required mechanically assisted ventilation and [...]

Case Presentation: A 24 year old Afro-Caribbean woman with no medical history presented with intermittent facial swelling of one month, several months of fatigue, anorexia and unintentional weight loss of 65 pounds. The swelling initially involved the lower face with gradual spread to bilateral peri-orbital areas. There was no urticaria, rash, dysphagia, dyspnea or visual [...]

Case Presentation: A 76 y.o. Caucasian male with a past medical history of heart failure with reduced ejection fraction (HFrEF), atrial fibrillation, HTN, and DVT/PE presented to the ED with a chief complaint of sharp, constant, LLQ abdominal pain and hematemesis x2 days. The patient was hemodynamically stable and exhibited diffuse abdominal tenderness on exam. [...]