Background: Complex non-pharmacologic interventions containing multiple, or bundled, components can successfully prevent and treat hospital-acquired delirium in older adults. However consistent implementation, and the measurement of compliance, of these bundled interventions can be challenging to sustain in hospital settings especially in presence of COVID-19. Developing workflows with a smaller sub-set of components that are feasible [...]

Background: Complex non-pharmacologic interventions containing multiple, or bundled, components can successfully prevent and treat hospital-acquired delirium in older adults. However consistent implementation, and the measurement of compliance, of these bundled interventions can be challenging to sustain in hospital settings especially in presence of COVID-19. Developing workflows with a smaller sub-set of components that are feasible [...]

Background: Recent guidelines include aspirin as an option to prevent venous thromboembolism (VTE) in selected patients undergoing hip or knee replacement surgery. However, the efficacy of aspirin after arthroplasty has not been well-defined, particularly in more contemporary patient populations. Objective: To compare rates of post-operative VTE between patients who received aspirin-only versus anticoagulants after hip [...]

Background: Approximately 15% of women in the United States aged 35-79 year are at high risk for developing breast cancer, however less than 0.2% of these women reported taking chemoprevention to reduce their risk. Objective of the study was to characterize the current utilization of chemoprevention agents among hospitalized women who are at higher risk [...]

Background: Reduced payments from Medicare related to high rates of hospital-acquired pressure injuries has prompted hospitals to invest in new technologies and strategies to improve wound care and prevention. While many hospitals have increased the purchase of skin care products such as prophylactic dressings, little is known about the association between these products and reductions [...]

Background: Reduced payments from Medicare related to high rates of hospital-acquired pressure injuries has prompted hospitals to invest in new technologies and strategies to improve wound care and prevention. While many hospitals have increased the purchase of skin care products such as prophylactic dressings, little is known about the association between these products and reductions [...]

Background: Transcatheter tricuspid valve procedures (TTVP) are used to manage tricuspid regurgitation, however these procedures are less common than other transcatheter valve procedures. Limited literature on TTVP exists, especially with regards to predictors of major outcomes. Atrial fibrillation (afib) is associated with increased mortality, stroke, cardiogenic shock, need for permanent pacemaker, AKI, major bleeding in [...]

Background: Delirium is associated with high morbidity and mortality in hospitalized older adults. Sleep is a modifiable risk factor for delirium. Eye masks (EMs) and earplugs (EPs) have been shown to improve sleep and effective reduce delirium in the ICU. This study examines the clinical usability of this intervention component in general medicine patients. We [...]

Background: Unexpected overnight adverse events are known to correlate with worse outcomes in inpatients.  Unfortunately, the exact occurrence and etiologies of such events have been less known.    Purpose: The aim of our study was to clarify the occurrence, etiologies of unexpected overnight adverse events and also propose the algorithm so that the catastrophic events [...]

Background: Sickle cell disease (SCD) is an autosomal recessive disease resulting in a broad range of functional and structural renal and cardiac alterations. Chronic kidney disease is with associated proteinuria, microalbuminuria and hemoglobinuria. Cardiac complications include diastolic heart disease, dysrhythmia and sudden death. In patients with advancing age, cardio-renal dysfunction can have substantial effects on [...]