Background: Frailty is linked to poor outcomes in older patients, especially those with multiple conditions. The electronic frailty index (eFI) is a validated tool based on the cumulative deficit model used to screen hospitalized patients at risk for poor outcomes1. The eFI relies on 35 ICD-10 codes associated with encounters across four domains (morbidity, sensory, [...]

Background: Frailty is a clinical syndrome characterized by vulnerability to stressors resulting from a loss of physiological reserve across multiple systems. Frailty is a common condition in older adults and is associated with disability, morbidity, increased healthcare utilization, and mortality. Frailty assessments derive from two major frameworks: the frailty phenotype and the deficit accumulation model. [...]

Background: Although the history of refeeding syndrome is long, few studies provide scientific information regarding refeeding syndrome in frail medical inpatients. In this study, we aimed to investigate the incidence, risk factors, and clinical implications of refeeding syndrome in frail hospitalized patients for acute medical problems. Methods: This was a single-center retrospective cohort study. Clinical [...]

Background: People living with HIV (PLWH) are now anticipated to have near-normal life expectancies. With increased longevity comes the higher burden of non-infectious comorbidities related to the chronic immune activation and premature telomere shortening in PLWH, ranging from dyslipidemia to osteoporosis [1]. Increased comorbidity burden can lead to polypharmacy, defined as the concurrent use of [...]

Background: Hospital readmissions within 30 days of discharge have gained national attention and account for more than $17 billion in avoidable U.S. Medicare expenditures each year. (1) In 2011 alone, there were approximately 3.3 million adult 30-day all-cause hospital readmissions, costing the US $41.3 billion.(2) As such, efforts have been made to create algorithms to [...]

Case Presentation: An 87yo woman with dementia presented with a large right adrenal mass consistent with pheochromocytoma with lymph node metastases based on biochemical testing and MIBG scan. Non-operative management with iobenguane-131 (Azedra) was considered because of her surgical risk. However, given her underlying dementia, comorbid conditions, and frailty, she was appropriately identified as high [...]

Background: Frailty is linked to poor outcomes in older patients, especially those with multiple conditions. The electronic frailty index (eFI) is a validated tool based on the cumulative deficit model used to screen hospitalized patients at risk for poor outcomes1. The eFI relies on 35 ICD-10 codes associated with encounters across four domains (morbidity, sensory, [...]