Case Presentation: Asenapine is widely acknowledged as a well-tolerated medication, exhibiting only infrequent severe adverse events1. The necessity of liver enzyme testing remains a topic without a unanimous consensus2. This case study discusses a patient who experienced significant liver damage upon initiating asenapine. As far as our understanding goes, this represents the initial documented instance [...]

Case Presentation: Diclofenac is a routinely prescribed non-steroidal anti-inflammatory agent in hospital with well-recognized hepatotoxic potential. However, there are only two reported cases of topical diclofenac-induced liver injury in literature. Herein, we describe a case of a 94-year-old man with Paget’s disease and osteoarthritis, who developed acute hepatotoxicity after four months of application of topical [...]

Case Presentation: A 57 years old female with insignificant past medical history presented to emergency department for right sided chest and back pain for one week that was associated with skin lesions under right breast and adjoining area on the back consistent with herpes zoster rash. She also reported epigastric pain, nausea and vomiting. She [...]

Case Presentation: A 71-year-old male with a PMH of CKD stage 3, CAD, BPH, atrial fibrillation, and diabetes mellitus presented to the ER for left foot swelling for the past 2-3 weeks. He had a history of left foot infection requiring debridement and skin grafts. Patient had recently tried a course of doxycycline and Keflex [...]

Case Presentation: A healthy 44-year-old woman with latent TB on isoniazid (INH) for 6 months was sent to the hospital by her primary care physician for elevated liver tests and right sided abdominal pain, anorexia, and jaundice for two weeks. She had normal liver tests prior to starting INH. She denied illicit drugs, alcohol or [...]

Case Presentation: A 70-year-old female with a medical history of fibromyalgia on Duloxetine, Systemic Lupus Erythematosus, and Paget’s disease admitted to the hospital for altered mentation was found to have elevated ALT 54 U/L, AST 63 U/L, normal bilirubin, and gamma glutamyl transferase. The mild elevation in Alkaline Phosphatase (ALP) 175 U/L was secondary to [...]