Case Presentation: A 66-year-old female with metastatic small cell lung cancer involving brain, liver, and bones was admitted via ED with generalized weakness, mild confusion, and decreased oral intake for 3 days. She was initiated on immunotherapy with immune checkpoint inhibitors, ipilimumab (human cytotoxic T-lymphocyte antigen 4 (CTLA-4)-blocking antibody) and nivolumab (a programmed death receptor-1 [...]

Case Presentation: A 69-year-old male with a past medical history of urothelial carcinoma status post left nephrectomy began immunotherapy and was started on Atezolizumab. He developed bilateral lower extremity weakness that began following his first dose. After 3 doses, in 02/2022, his lower extremity weakness worsened to the point where he could not walk. A [...]

Case Presentation: We report the case of a 45-year-old female with stage IA triple-negative breast cancer treated with neoadjuvant chemotherapy and pembrolizumab who developed secondary adrenal insufficiency due to adrenocorticotropic hormone (ACTH) deficiency six months after stopping the immune checkpoint inhibitor. She presented with persistent nausea, vomiting, weight loss, and altered mental status. Laboratory results [...]